Choi Kyu-jin debut as an actor in 2013 with a small role in the KBS2 series Ad Genius Lee Tae-baek. In 2017, he appeared in the tvN drama Buam-dong Revenge Club. In 2018, he was cast in supporting roles in tvN’s The Crowned Clown and OCN’s Class of Lies. That same year, he starred alongside Jeon Hyo-sung in the web series Green to My Heart. In 2020, he joined the MBC dark mystery-comedy drama United Effort to Accomplish One Thing, which gave him a Best New Actor nomination at the MBC Drama Awards.