Oh Dong-min debuted as an actor in 2008 through the play Nabi’s Hamlet. That same year, he bagged a small role in the KBS1 miniseries Lottery Trio. He then joined the 2010 SBS melodrama Bad Guy. He also slowly made a name for himself in the indie scene with his starring roles in several short films such as Nothing to Live for in 2014 and Hatred in 2016. In 2017, he was cast in his first feature film titled How to Breathe Underwater. In 2018, he played a doctor in the SBS series Heart Surgeons. In 2019, he became part of the hit Netflix zombie sageuk Kingdom. In 2020, he starred in the web dramas Romance Bible and My Fuxxxxx Romance. Also in 2020, he led the films Killer Swell: Our Space and One Blue Rainy Day.