Do-hee broke into the entertainment industry as a member of the South Korean girl group Tiny-G in 2012. She served as the group’s lead vocalist. They released their self-titled debut single in August 2012. The group unofficially disbanded in 2015.

Do-hee landed her first acting role in the tvN series Answer Me 1994 in 2013. Her work in the drama won her Best New Actress as well as Best Couple with Kim Sung-kyun at the 7th Korea Drama Awards. She also scored Best New Actress nominations at the 50th Baeksang Arts Awards and the 3rd APAN Star Awards. In 2017, she played a bully in the eight-episode KBS2 series Lingerie Girls’ Generation. In 2018, she acted supporting roles in OCN’s Longing Heart and JTBC’s My ID Is Gangnam Beauty and Clean with Passion for Now. In 2020, she joined the main cast of the KBS2 coming-of-age drama How to Buy a Friend.

Do-hee has an older brother named Min Do-joon.