Ji Eun-sung made his acting debut in the 2013 JTBC sageuk Cruel Palace – War of the Flowers. In 2014, he appeared in tvN’s Three Musketeers and in SBS’s A Mother’s Choice. In 2015, he became part of the MBC series Shine or Go Crazy and the web drama Never Die. In 2016, he joined the main cast of the KBS2 morning soap opera TV Novel: My Mind’s Flower Rain. In 2017, he played a supporting role in the MBC daily drama Reverse. That same year, he starred in the web series Listen to Her Heart. In 2019, he portrayed the young counterpart of Jang Hyuk’s character in JTBC’s My Country: The New Age.

Ji Eun-sung studied visual design at Gwangju University.