Kim Ji-eun made her acting debut in the 2015 film Tattoo. In 2018, she had appearances in SBS’s Tale of a Good Witch, KBS2’s Lovely Horribly, and MBC’s Red Moon, Blue Sun. That same year, she landed a small role in the crime drama film The Drug King. In 2019, she starred in the web series I Have Three Boyfriends, which gave her a Best Actress nomination at the 2020 Seoul International Drama Awards. She then played a supporting character in the OCN horror-thriller drama Hell Is Other People. In 2021, she acted alongside Namgoong Min and Park Ha-sun in MBC’s The Veil, which won her Best New Actress at the MBC Drama Awards. She was later cast as the female lead in the 2022 SBS series Again My Life.

Kim Ji-eun studied theater at Cheongju University.