Kyung Su-jin made her acting debut in the 2011 SBS series New Gisaeng Story. In 2013, she played the young counterpart of Sohn Ye-jin’s character in KBS2’s Shark. That same year, she landed her first leading role in the KBS2 daily series Eun-hee. Her performance in both dramas won her Best New Actress at the KBS Drama Awards. In 2015, she joined the main cast of the KBS2 weekend series Bluebird’s House, which earned her an Excellence Award nomination at the KBS Drama Awards. In 2016, she was nominated for another Excellence Award at the MBC Drama Awards for the coming-of-age sports drama Weightlifting Fairy Kim Bok-ju. In 2017, she portrayed a woman with a split personality in OCN’s fantasy rom-com Meloholic. In 2020, she starred in another OCN drama called Train, opposite Yoon Shi-yoon. In 2021, she acted alongside Lee Seung-gi in tvN’s hit crime thriller Mouse.

Kyung Su-jin attended Namseoul University.