Park Hee-bon debuted with M.I.L.K. under the mononym Jaeyoung. The group released their first and only album called With Freshness in December 2001. In 2002, they were nominated for Best New Group at the 2002 Mnet Music Video Festival for the song Come to Me. The group disbanded in 2003 following the departure of one of its members, Bae Yu-mi.

Park Hee-bon used her birth name upon transitioning into acting. Some of her early works are the sitcom Nonstop 6 and the rom-com Billie Jean, Look at Me, which both aired on MBC. In 2010, she acted alongside Kim Tae-hee and Yang Dong-geun in the sports film Grand Prix. That same year, she released her first solo single titled Twenty-two. In 2012, she appeared in the KBS2 sitcom Family, which was followed by a supporting role in SBS’s Master’s Sun in 2013. In 2014, she became part of the MBC drama Fated to Love You. In 2015, she joined the main cast of the tvN romantic comedy series Bubblegum. In 2019, she starred in the SBS noir drama Secret Boutique. In 2021, she was cast in tvN’s Happiness.

Park Hee-bon majored in film arts at Sejong University. She married director and screenwriter Yoon Se-young in June 2016.