Park Ji-hyun debuted as an actress in 2017 with appearances in the film Control and in SBS’s Saimdang, Light’s Diary and MBC’s The King Loves. In 2018, she starred in the horror film Gonjinam: Haunted Asylum, which earned her Best New Actress nominations at the 39th Blue Dragon Film Awards and the 24th Chunsa Film Art Awards. In 2019, she played a supporting role in the MBC sageuk Rookie Historian Gu Hae-ryung, which scored her an Excellence Award nomination at the MBC Drama Awards. That same year, she returned on the big screen in the action horror film The Divine Fury. In 2020, she became part of the main cast of the SBS series Do You Like Brahms, which gave her a Best New Actress nomination at the SBS Drama Awards. In 2021, she acted alongside Kim Go-eun and Ahn Bo-hyun in tvN’s Yumi’s Cells.

Park Ji-hyun attended the Hankuk University of Foreign Studies.