Chun Ho-jin forayed in the entertainment industry in 1983. He won the Best New Actor for TV at the 28th Baeksang Arts Awards in 1992 for his work in the long-running KBS drama Love on a Jujube Tree. He was then nominated as Best Supporting Actor at the 41st and 44th Grand Bell Awards for the 2004 heist movie The Big Swindle and the 2006 neo-noir action film A Dirty Carnival, respectively. In 2012, Chun Ho-jin was cast in the KBS2 family drama My Daughter Seo-young, which recorded a peak viewership rating of 47.6 percent. His portrayal of the titular character’s father in the drama earned him various acting award nominations. In 2017, he won the Daesang at the KBS Drama Awards for his role as a bankrupt and struggling father of four children in the family series My Golden Life. In 2020, he was cast in the KBS2 family drama Once Again as a father of four adult siblings who struggle with matters of the heart and life in general. He once again won the Daesang at the KBS Drama Awards for his performance in the series. Due to his memorable portrayal of father roles in various dramas, Chun Ho-jin earned the nickname “the national father.”

Chun Ho-jin has been married since 1986. His father is former professional wrestler Chun Gyu-duk, who became a senior advisor in the Korean Professional Wrestling Association following his retirement in 1985.