Lee Bom-sori first established herself as a theater actress with appearances in several musicals such as Roly Poly in 2012, Romeo and Juliet in 2017, and Marie Curie in 2020. She made her screen debut in 2016 with a minor role in the SBS series Doctors. In 2018, she joined the KBS2 drama Miracle That We Met. She then landed a supporting role in another KBS2 series called Justice in 2019. In 2022, she played a police officer in the tvN fantasy romance Link: Eat, Love, Kill.

Lee Bom-sori attended Chung-Ang University’s theater department.